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X-linked lymphoproliferative disease

2 OMIM references -
2 associated genes
8 signs/symptoms

PROTEIN INTERACTIONS: 1

Primary peritoneal carcinoma

1 associated gene
9 signs/symptoms

X-linked lymphoproliferative disease

Primary peritoneal carcinoma

SH2D1A	(UniProt - OMIM)		BRCA1	(UniProt - OMIM)
XIAP	(UniProt - OMIM)


INTERACTOME ASSOCIATIONS (click on a score value to see the evidence)	XIAP	(0.68)	BRCA1

Citations in the biomedical literature:

X-linked lymphoproliferative disease		Primary peritoneal carcinoma
	Synonym(s): - Duncan disease - Purtilo syndrome - XLP		Synonym(s): - EOPPC - Extra-ovarian primary peritoneal carcinoma - PPC - Primary peritoneal serous carcinoma - Serous surface papillary carcinoma

	Classification (Orphanet): - Rare genetic disease - Rare immune disease - Rare oncologic disease		Classification (Orphanet): - Rare abdominal surgical disease - Rare oncologic disease

	Classification (ICD10): - Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism -		Classification (ICD10): - Neoplasms -

	Epidemiological data: Class of prevalence: <1 / 1 000 000 Average age onset: childhood Average age of death: - Type of inheritance: x-linked recessive		Epidemiological data: Class of prevalence: unknown Average age onset: adulthood Average age of death: normal Type of inheritance: unknown

	External references: 2 OMIM references - 1 MeSH reference: D008232		External references: No OMIM references No MeSH references

X-linked lymphoproliferative disease		Primary peritoneal carcinoma
	Very frequent - T-cell deficiency / cellular immunity deficiency - X-linked recessive inheritance Frequent - Agammaglobulinemia / hypogammaglobulinemia / B-cell deficiency - Hepatomegaly / liver enlargement (excluding storage disease) - Lymphadenopathy / polyadenopathies - Lymphoma - Splenomegaly Occasional - Anaemia		Very frequent - Acute abdominal pain / colic - Anomalies of the abdominal wall - Constipation - Nausea / vomiting / regurgitation / merycism / hyperemesis - Neoplasms / tumors - Ovary / Fallopian tube neoplasm / tumor / carcinoma / cancer (excl. teratoma / germinoma) - Peritoneal diseases - Weight loss / loss of appetite / break in weight curve / general health alteration Occasional - Early death / lethality